Certified Nurses Operating Room (CNOR) Exam 2025 – 400 Free Practice Questions to Pass the Exam

The initial symptom of local anesthesia toxicity typically presents as central nervous system (CNS) excitation rather than hypotension or cardiovascular changes, which are more likely to follow as the toxicity progresses. In fact, CNS symptoms can escalate from initial findings such as restlessness, dizziness, or tinnitus to more severe manifestations like seizures or decreased responsiveness.

While hypertension may occur later in the course of systemic toxicity as a compensatory response or in cases of significant agitation, the initial signs reflect a more heightened CNS activity. Often, the first noticeable signs involve symptoms like excitement or anxiety, leading to potential seizures as local anesthesia levels rise in the bloodstream.

Understanding the initial symptoms is crucial for nursing professionals in the operating room setting, as recognizing local anesthesia toxicity early can prompt timely intervention and mitigation of adverse effects.